Preparing for Life: Plasma Proteome Changes and Immune System Development During the First Week of Human Life

Preparing for Life: Plasma Proteome Changes and Immune System Development During the First Week of Human Life

Neonates have heightened susceptibility to infections. The biological mechanisms are incompletely understood but thought to be related to age-specific adaptations in immunity due to resource constraints during immune system development and growth. We present here an extended analysis of our proteomi...

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Bibliographic Details
Main Authors: Tue Bjerg Bennike, Benoit Fatou, Asimenia Angelidou, Joann Diray-Arce, Reza Falsafi, Rebecca Ford, Erin E. Gill, Simon D. van Haren, Olubukola T. Idoko, Amy H. Lee, Rym Ben-Othman, William S. Pomat, Casey P. Shannon, Kinga K. Smolen, Scott J. Tebbutt, Al Ozonoff, Peter C. Richmond, Anita H. J. van den Biggelaar, Robert E. W. Hancock, Beate Kampmann, Tobias R. Kollmann, Ofer Levy, Hanno Steen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
ontogeny
complement
innate immune system
immunoglobulin
proteomics
inhibitors
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.578505/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.578505/full

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