Bile Acids and Cancer: Direct and Environmental-Dependent Effects

Bile acids (BAs) regulate the absorption of fat-soluble vitamins, cholesterol and lipids but have also a key role as signaling molecules and in the modulation of epithelial cell proliferation, gene expression and metabolism. These homeostatic pathways, when disrupted, are able to promote local infla...

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Bibliographic Details
Main Authors: Agostino Di Ciaula, David Q.-H. Wang, Emilio Molina-Molina, Raquel Lunardi Baccetto, Giuseppe Calamita, Vincenzo O. Palmieri, Piero Portincasa
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Annals of Hepatology
Subjects:
FXR
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119310476