MST3 Involvement in Na<sup>+</sup> and K<sup>+</sup> Homeostasis with Increasing Dietary Potassium Intake

MST3 Involvement in Na<sup>+</sup> and K<sup>+</sup> Homeostasis with Increasing Dietary Potassium Intake

K<sup>+</sup> loading inhibits NKCC2 (Na-K-Cl cotransporter) and NCC (Na-Cl cotransporter) in the early distal tubules, resulting in Na<sup>+</sup> delivery to the late distal convoluted tubules (DCTs). In the DCTs, Na<sup>+</sup> entry through ENaC (epithelial Na...

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Bibliographic Details
Main Authors: Chee-Hong Chan, Sheng-Nan Wu, Bo-Ying Bao, Houng-Wei Li, Te-Ling Lu
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
MST3
STK24
high potassium
ENaC
NKCC2
SPAK
Online Access:https://www.mdpi.com/1422-0067/22/3/999

Internet

https://www.mdpi.com/1422-0067/22/3/999

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