G-computation and machine learning for estimating the causal effects of binary exposure statuses on binary outcomes

Abstract In clinical research, there is a growing interest in the use of propensity score-based methods to estimate causal effects. G-computation is an alternative because of its high statistical power. Machine learning is also increasingly used because of its possible robustness to model misspecifi...

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Bibliographic Details
Main Authors: Florent Le Borgne, Arthur Chatton, Maxime Léger, Rémi Lenain, Yohann Foucher
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81110-0