The encapsulation of hemagglutinin in protein bodies achieves a stronger immune response in mice than the soluble antigen

The encapsulation of hemagglutinin in protein bodies achieves a stronger immune response in mice than the soluble antigen

Zein is a water-insoluble polymer from maize seeds that has been widely used to produce carrier particles for the delivery of therapeutic molecules. We encapsulated a recombinant model vaccine antigen in newly formed zein bodies in planta by generating a fusion construct comprising the ectodomain of...

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Bibliographic Details
Main Authors: Anna eHofbauer, Stanislav eMelnik, Marc eTschofen, Elsa eArcalis, Hoang ePhan, Ulrike eGresch, Johannes eLampel, Udo eConrad, Eva eStoger
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Plant Science
Subjects:
Molecular Farming
recombinant protein
subcellular targeting
Protein Bodies
Recombinant vaccine
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpls.2016.00142/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpls.2016.00142/full

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