Suppression of Tumor Growth, Metastasis, and Signaling Pathways by Reducing FOXM1 Activity in Triple Negative Breast Cancer

Suppression of Tumor Growth, Metastasis, and Signaling Pathways by Reducing FOXM1 Activity in Triple Negative Breast Cancer

Metastasis-related complications account for the overwhelming majority of breast cancer mortalities. Triple negative breast cancer (TNBC), the most aggressive breast cancer subtype, has a high propensity to metastasize to distant organs, leading to poor patient survival. The forkhead transcription f...

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Bibliographic Details
Main Authors: Parama Dey, Alexander Wang, Yvonne Ziegler, Sung Hoon Kim, Dorraya El-Ashry, John A. Katzenellenbogen, Benita S. Katzenellenbogen
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
triple negative breast cancer
migration
invasion
metastasis
FOXM1
EMT
Online Access:https://www.mdpi.com/2072-6694/12/9/2677

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