Sex-Based Mhrt Methylation Chromatinizes MeCP2 in the Heart

Sex-Based Mhrt Methylation Chromatinizes MeCP2 in the Heart

Summary: In the heart, primary microRNA-208b (pri-miR-208b) and Myheart (Mhrt) are long non-coding RNAs (lncRNAs) encoded by the cardiac myosin heavy chain genes. Although preclinical studies have shown that lncRNAs regulate gene expression and are protective for pathological hypertrophy, the mechan...

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Bibliographic Details
Main Authors: Harikrishnan K.N., Jun Okabe, Prabhu Mathiyalagan, Abdul Waheed Khan, Sameer A. Jadaan, Gulcan Sarila, Mark Ziemann, Ishant Khurana, Scott S. Maxwell, Xiao-Jun Du, Assam El-Osta
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219302147

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http://www.sciencedirect.com/science/article/pii/S2589004219302147

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