Role of a genetic polymorphism in the corticotropin-releasing factor receptor 1 gene in alcohol drinking and seeking behaviors of Marchigian Sardinian alcohol-preferring (msP) rats

Role of a genetic polymorphism in the corticotropin-releasing factor receptor 1 gene in alcohol drinking and seeking behaviors of Marchigian Sardinian alcohol-preferring (msP) rats

Marchigian Sardinian alcohol-preferring (msP) rats exhibit innate preference for alcohol, are highly sensitive to stress and stress-induced alcohol seeking. Genetic analysis showed that over-expression of the corticotropin-releasing factor (CRF) system of msP rats is correlated with the presence of...

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Bibliographic Details
Main Authors: Lydia Ojonemile Ayanwuyi, Francisca eCarvajal, Jose eLerma-Cabrera, Esi eDomi, Karl eBjork, Massimo eUbaldi, Markus eHeilig, Marisa eRoberto, Roberto eCiccocioppo, Andrea eCippitelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Psychiatry
Subjects:
Yohimbine
CRF
SNP
self-administration
relapse
MSP
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00023/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00023/full

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