Biosafety evaluation of culture-expanded human chondrocytes with growth factor cocktail: a preclinical study

Abstract The scarcity of chondrocytes is a major challenge for cartilage tissue engineering. Monolayer expansion is necessary to amplify the limited number of chondrocytes needed for clinical application. Growth factors are often added to improve monolayer culture conditions, promoting proliferation...

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Bibliographic Details
Main Authors: Maimonah-Eissa Al-Masawa, Wan Safwani Wan Kamarul Zaman, Kien-Hui Chua
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78395-y