A case of congenital autonomous thyroid adenoma with a somatic activating gene mutation in the thyroid-stimulating hormone receptor

A case of congenital autonomous thyroid adenoma with a somatic activating gene mutation in the thyroid-stimulating hormone receptor

We report here a male case of autonomous adenoma (AA) in the thyroid that was caused by a somatic heterozygous mutation in the thyroid-stimulating hormone receptor (TSHR) gene at codon 453, which encodes the second transmembrane domain of the protein. This activating mutation of TSHR induced an incr...

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Bibliographic Details
Main Authors: Kotaro Tomonaga, Kazunori Tahara, Toshihiko Watanabe, Michinobu Ohno, Katsuhiro Ogawa, Mai Kutsukake, Akihiro Fujino, Tomoro Hishiki, Kenichi Kinjyo, Reiko Horikawa, Noriyuki Katsumata, Yutaka Kanamori
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Journal of Pediatric Surgery Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213576618302306

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http://www.sciencedirect.com/science/article/pii/S2213576618302306

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