Development of a toolkit for piggyBac-mediated integrative transfection of the human filarial parasite Brugia malayi.

BACKGROUND:The human filarial parasites cause diseases that are among the most important causes of morbidity in the developing world. The elimination programs targeting these infections rely on a limited number of drugs, making the identification of new chemotherapeutic agents a high priority. The s...

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Bibliographic Details
Main Authors: Canhui Liu, Amruta S Mhashilkar, Johan Chabanon, Shulin Xu, Sara Lustigman, John H Adams, Thomas R Unnasch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5983866?pdf=render