Brugia malayi microfilariae adhere to human vascular endothelial cells in a C3-dependent manner.

Brugia malayi microfilariae adhere to human vascular endothelial cells in a C3-dependent manner.

Brugia malayi causes the human tropical disease, lymphatic filariasis. Microfilariae (Mf) of this nematode live in the bloodstream and are ingested by a feeding mosquito vector. Interestingly, in a remarkable co-evolutionary adaptation, Mf appearance in the peripheral blood follows a circadian perio...

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Bibliographic Details
Main Authors: Jan-Hendrik Schroeder, David McCarthy, Tadge Szestak, Darren A Cook, Mark J Taylor, Alister G Craig, Charlotte Lawson, Rachel A Lawrence
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5436873?pdf=render

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http://europepmc.org/articles/PMC5436873?pdf=render

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