Optimising Large Animal Models of Sustained Atrial Fibrillation: Relevance of the Critical Mass Hypothesis

Optimising Large Animal Models of Sustained Atrial Fibrillation: Relevance of the Critical Mass Hypothesis

BackgroundLarge animal models play an important role in our understanding of the pathophysiology of atrial fibrillation (AF). Our aim was to determine whether prospectively collected baseline variables could predict the development of sustained AF in sheep, thereby reducing the number of animals req...

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Bibliographic Details
Main Authors: Nathan C. Denham, Charles M. Pearman, George W. P. Madders, Charlotte E. R. Smith, Andrew W. Trafford, Katharine M. Dibb
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Physiology
Subjects:
atrial
fibrillation
critical
mass
hypothesis
pathophysiology
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.690897/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.690897/full

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