Desensitization of Capsaicin-Sensitive Afferents Accelerates Early Tumor Growth via Increased Vascular Leakage in a Murine Model of Triple Negative Breast Cancer

Desensitization of Capsaicin-Sensitive Afferents Accelerates Early Tumor Growth via Increased Vascular Leakage in a Murine Model of Triple Negative Breast Cancer

There is growing interest in the role of nerve-driven mechanisms in tumorigenesis and tumor growth. Capsaicin-sensitive afferents have been previously shown to possess antitumoral and immune-regulatory properties, the mechanism of which is currently poorly understood. In this study, we have assessed...

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Bibliographic Details
Main Authors: Noémi Bencze, Csaba Schvarcz, Gábor Kriszta, Lea Danics, Éva Szőke, Péter Balogh, Árpád Szállási, Péter Hamar, Zsuzsanna Helyes, Bálint Botz
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
breast cancer
in vivo imaging
4T1 breast cancer
vascular leakage
capsaicin sensitive sensory nerves
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.685297/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.685297/full

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