Most small bowel cancers are revealed by a complication
ABSTRACT Objective To characterize the pattern of primary small bowel cancers in a tertiary East-European hospital. Methods A retrospective study of patients with small bowel cancers admitted to a tertiary emergency center, over the past 15 years. Results There were 57 patients with small bowe...
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doaj-9ba0107a0ccc4a6f9b4c8f0c612babfe2020-11-25T01:25:39ZengInstituto Israelita de Ensino e Pesquisa Albert EinsteinEinstein (São Paulo)2317-638513450050510.1590/S1679-45082015AO3380S1679-45082015000400500Most small bowel cancers are revealed by a complicationIonut NegoiSorin PaunSorin HostiucBodgan StoicaIoan TanaseRuxandra Irina NegoiMircea BeuranABSTRACT Objective To characterize the pattern of primary small bowel cancers in a tertiary East-European hospital. Methods A retrospective study of patients with small bowel cancers admitted to a tertiary emergency center, over the past 15 years. Results There were 57 patients with small bowel cancer, representing 0.039% of admissions and 0.059% of laparotomies. There were 37 (64.9%) men, mean age of 58 years; and 72 years for females. Out of 57 patients, 48 (84.2%) were admitted due to an emergency situation: obstruction in 21 (38.9%), perforation in 17 (31.5%), upper gastrointestinal bleeding in 8 (14.8%), and lower gastrointestinal bleeding in 2 (3.7%). There were 10 (17.5%) duodenal tumors, 21 (36.8%) jejunal tumors and 26 (45.6%) ileal tumors. The most frequent neoplasms were gastrointestinal stromal tumor in 24 patients (42.1%), adenocarcinoma in 19 (33.3%), lymphoma in 8 (14%), and carcinoids in 2 (3.5%). The prevalence of duodenal adenocarcinoma was 14.55 times greater than that of the small bowel, and the prevalence of duodenal stromal tumors was 1.818 time greater than that of the small bowel. Obstruction was the complication in adenocarcinoma in 57.9% of cases, and perforation was the major local complication (47.8%) in stromal tumors. Conclusion Primary small bowel cancers are usually diagnosed at advanced stages, and revealed by a local complication of the tumor. Their surgical management in emergency setting is associated to significant morbidity and mortality rates.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000400500&lng=en&tlng=enIntestino delgado/patologiaNeoplasiasEmergências |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ionut Negoi Sorin Paun Sorin Hostiuc Bodgan Stoica Ioan Tanase Ruxandra Irina Negoi Mircea Beuran |
spellingShingle |
Ionut Negoi Sorin Paun Sorin Hostiuc Bodgan Stoica Ioan Tanase Ruxandra Irina Negoi Mircea Beuran Most small bowel cancers are revealed by a complication Einstein (São Paulo) Intestino delgado/patologia Neoplasias Emergências |
author_facet |
Ionut Negoi Sorin Paun Sorin Hostiuc Bodgan Stoica Ioan Tanase Ruxandra Irina Negoi Mircea Beuran |
author_sort |
Ionut Negoi |
title |
Most small bowel cancers are revealed by a complication |
title_short |
Most small bowel cancers are revealed by a complication |
title_full |
Most small bowel cancers are revealed by a complication |
title_fullStr |
Most small bowel cancers are revealed by a complication |
title_full_unstemmed |
Most small bowel cancers are revealed by a complication |
title_sort |
most small bowel cancers are revealed by a complication |
publisher |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
series |
Einstein (São Paulo) |
issn |
2317-6385 |
description |
ABSTRACT Objective To characterize the pattern of primary small bowel cancers in a tertiary East-European hospital. Methods A retrospective study of patients with small bowel cancers admitted to a tertiary emergency center, over the past 15 years. Results There were 57 patients with small bowel cancer, representing 0.039% of admissions and 0.059% of laparotomies. There were 37 (64.9%) men, mean age of 58 years; and 72 years for females. Out of 57 patients, 48 (84.2%) were admitted due to an emergency situation: obstruction in 21 (38.9%), perforation in 17 (31.5%), upper gastrointestinal bleeding in 8 (14.8%), and lower gastrointestinal bleeding in 2 (3.7%). There were 10 (17.5%) duodenal tumors, 21 (36.8%) jejunal tumors and 26 (45.6%) ileal tumors. The most frequent neoplasms were gastrointestinal stromal tumor in 24 patients (42.1%), adenocarcinoma in 19 (33.3%), lymphoma in 8 (14%), and carcinoids in 2 (3.5%). The prevalence of duodenal adenocarcinoma was 14.55 times greater than that of the small bowel, and the prevalence of duodenal stromal tumors was 1.818 time greater than that of the small bowel. Obstruction was the complication in adenocarcinoma in 57.9% of cases, and perforation was the major local complication (47.8%) in stromal tumors. Conclusion Primary small bowel cancers are usually diagnosed at advanced stages, and revealed by a local complication of the tumor. Their surgical management in emergency setting is associated to significant morbidity and mortality rates. |
topic |
Intestino delgado/patologia Neoplasias Emergências |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000400500&lng=en&tlng=en |
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