In Vivo Protective Effects of Diosgenin against Doxorubicin-Induced Cardiotoxicity

Doxorubicin (DOX) induces oxidative stress leading to cardiotoxicity. Diosgenin, a steroidal saponin of Dioscorea opposita, has been reported to have antioxidant activity. Our study was aimed to find out the protective effect of diosgenin against DOX-induced cardiotoxicity in mice. DOX treatment led...

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Bibliographic Details
Main Authors: Chih-Tai Chen, Zhi-Hong Wang, Cheng-Chin Hsu, Hui-Hsuan Lin, Jing-Hsien Chen
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Nutrients
Subjects:
Online Access:http://www.mdpi.com/2072-6643/7/6/4938