Detection of activating mutations in RAS/RAF/MEK/ERK and JAK/STAT signaling pathways

Detection of activating mutations in RAS/RAF/MEK/ERK and JAK/STAT signaling pathways

Issue.The study of activating mutations (NRAS,KRAS,FLT3,JAK2,CRLF2genes) of RAS/RAF/MEK/ERK and JAK/STAT signaling pathways in B-cell acute lymphoblastic leukemia (B-ALL) in adult patients which are included in Russian multicenter clinical trials. Materials and methods.Within the multicenter stud...

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Main Authors: K. I. Zarubina, E. N. Parovichnikova, V. L. Surin, O. S. Pshenichnikova, O. A. Gavrilina, G. A. Isinova, V. V. Troitskaia, A. N. Sokolov, I. V. Gal’tseva, N. M. Kapranov, Iu. O. Davydova, T. N. Obukhova, A. B. Sudarikov, V. G. Savchenko
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2020-09-01
Series:Терапевтический архив
Subjects:
b-cell acute lymphoblastic leukemia
bcr-abl1-positive b-all
bcr-abl1-negative b-all
signaling pathways
activating mutations of nras
kras
flt3
jak2
crlf2 genes
Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/43121/pdf

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https://ter-arkhiv.ru/0040-3660/article/viewFile/43121/pdf

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