Generation and differentiation of chemically derived hepatic progenitors from mouse primary hepatocytes

Summary: This protocol describes the generation of bipotent chemically derived hepatic progenitors (mCdHs) from mouse primary hepatocytes and their subsequent differentiation into either hepatic or cholangiocytic lineages. The reprogrammed mCdHs have a high proliferation capacity and express progeni...

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Bibliographic Details
Main Authors: Yohan Kim, Jaemin Jeong, Dongho Choi
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721005463