The role of recombination for the coevolutionary dynamics of HIV and the immune response.

The evolutionary implications of recombination in HIV remain not fully understood. A plausible effect could be an enhancement of immune escape from cytotoxic T lymphocytes (CTLs). In order to test this hypothesis, we constructed a population dynamic model of immune escape in HIV and examined the vir...

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Bibliographic Details
Main Authors: Rafal Mostowy, Roger D Kouyos, David Fouchet, Sebastian Bonhoeffer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21364750/pdf/?tool=EBI