KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA.

KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA.

Host signal-transduction pathways are intimately involved in the switch between latency and productive infection of herpes viruses. As with other herpes viruses, infection by Kaposi's sarcoma herpesvirus (KSHV) displays these two phases. During latency only few viral genes are expressed, while...

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Bibliographic Details
Main Authors: Fang Cheng, Magdalena Weidner-Glunde, Markku Varjosalo, Eeva-Marja Rainio, Anne Lehtonen, Thomas F Schulz, Päivi J Koskinen, Jussi Taipale, Päivi M Ojala
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19266083/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19266083/?tool=EBI

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