Synthesis, Characterization, and In Vivo Anti-Cancer Activity of New Metal Complexes Derived from Isatin-<i>N</i>(4)antipyrinethiosemicarbazone Ligand Against Ehrlich Ascites Carcinoma Cells

Synthesis, Characterization, and In Vivo Anti-Cancer Activity of New Metal Complexes Derived from Isatin-<i>N</i>(4)antipyrinethiosemicarbazone Ligand Against Ehrlich Ascites Carcinoma Cells

The current study aimed to synthesize new metal coordination complexes with potential biomedical applications. Metal complexes were prepared via the reaction of isatin-<i>N</i>(4)anti- pyrinethiosemicarbazone ligand <b>1</b> with Cu(II), Ni(II), Co(II), Zn(II), and Fe(III) io...

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Bibliographic Details
Main Authors: Fathy El-Saied, Bishoy El-Aarag, Tarek Salem, Ghada Said, Shaden A. M. Khalifa, Hesham R. El-Seedi
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Molecules
Subjects:
metal complexes
isatin-<i>N</i>(4)antipyrinethiosemicarbazone
Ehrlich ascites carcinoma
tumor volume
VEGF
caspase-7
Online Access:https://www.mdpi.com/1420-3049/24/18/3313

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https://www.mdpi.com/1420-3049/24/18/3313

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