Travel and the emergence of high-level drug resistance in Plasmodium falciparum in southwest Uganda: results from a population-based study

Travel and the emergence of high-level drug resistance in Plasmodium falciparum in southwest Uganda: results from a population-based study

Abstract Background The I164L mutation on the dhfr gene confers high level resistance to sulfadoxine–pyrimethamine (SP) but it is rare in Africa except in a cluster of reports where prevalence >10% in highland areas of southwest Uganda and eastern Rwanda. The occurrence of the dhfr I164L mutation...

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Bibliographic Details
Main Authors: Caroline A. Lynch, Richard Pearce, Hirva Pota, Connie Egwang, Thomas Egwang, Amit Bhasin, Jonathan Cox, Tarekegn A. Abeku, Cally Roper
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Malaria Journal
Subjects:
Malaria
dhfr
Sulfadoxine–pyrimethamine (SP)
Migration
Travel
Drug resistance
Online Access:http://link.springer.com/article/10.1186/s12936-017-1812-1

Internet

http://link.springer.com/article/10.1186/s12936-017-1812-1

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