Mutations of C-reactive protein (CRP) -286 SNP, APC and p53 in colorectal cancer: implication for a CRP-Wnt crosstalk.

C-reactive protein (CRP) is an established marker of inflammation with pattern-recognition receptor-like activities. Despite the close association of the serum level of CRP with the risk and prognosis of several types of cancer, it remains elusive whether CRP contributes directly to tumorigenesis or...

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Main Authors: Hai-Xiang Su, Hai-Hong Zhou, Ming-Yu Wang, Jin Cheng, Shi-Chao Zhang, Feng Hui, Xue-Zhong Chen, Shan-Hui Liu, Qin-Jiang Liu, Zi-Jiang Zhu, Qing-Rong Hu, Yi Wu, Shang-Rong Ji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4099363?pdf=render