β2-adrenoceptors are essential for desipramine, venlafaxine or reboxetine action in neuropathic pain

β2-adrenoceptors are essential for desipramine, venlafaxine or reboxetine action in neuropathic pain

Neuropathic pain is a disease caused by a lesion or dysfunction of the nervous system. Antidepressants or anticonvulsants are presently the best available treatments. The mechanism by which antidepressants relieve neuropathic pain remains poorly understood. Using pharmacological and transgenic appro...

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Bibliographic Details
Main Authors: Ipek Yalcin, Luc-Henri Tessier, Nathalie Petit-Demoulière, Stéphane Doridot, Lutz Hein, Marie-José Freund-Mercier, Michel Barrot
Format: Article
Language:English
Published: Elsevier 2009-03-01
Series:Neurobiology of Disease
Subjects:
Antiallodynic
Antidepressant
Beta2 adrenoceptor
Alpha2 adrenoceptor
Gabapentin
Neuropathic pain
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108002817

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http://www.sciencedirect.com/science/article/pii/S0969996108002817

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