Development of in vitro 3D TissueFlex® islet model for diabetic drug efficacy testing.

Increasing individuals diagnosed with type II diabetes pose a strong demand for the development of more effective anti-diabetic drugs. However, expensive, ethically controversial animal-based screening for anti-diabetic compounds is not always predictive of the human response. The use of in vitro ce...

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Bibliographic Details
Main Authors: Zhaohui Li, He Sun, Jianbin Zhang, Haijiao Zhang, Fanyu Meng, Zhanfeng Cui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3744493?pdf=render