Detrimental Effects of HMGB-1 Require Microglial-Astroglial Interaction: Implications for the Status Epilepticus -Induced Neuroinflammation

Detrimental Effects of HMGB-1 Require Microglial-Astroglial Interaction: Implications for the Status Epilepticus -Induced Neuroinflammation

Temporal Lobe Epilepsy (TLE) is the most common form of human epilepsy and available treatments with antiepileptic drugs are not disease-modifying therapies. The neuroinflammation, neuronal death and exacerbated plasticity that occur during the silent period, following the initial precipitating even...

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Bibliographic Details
Main Authors: Gerardo Rosciszewski, Vanesa Cadena, Jerónimo Auzmendi, María Belén Cieri, Jerónimo Lukin, Alicia R. Rossi, Veronica Murta, Alejandro Villarreal, Analia Reinés, Flávia C. A. Gomes, Alberto Javier Ramos
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
epilepsy
glia
inflammation
seizures
neuronal death
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00380/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2019.00380/full

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