Leishmania infantum Asparagine Synthetase A Is Dispensable for Parasites Survival and Infectivity.
A growing interest in asparagine (Asn) metabolism has currently been observed in cancer and infection fields. Asparagine synthetase (AS) is responsible for the conversion of aspartate into Asn in an ATP-dependent manner, using ammonia or glutamine as a nitrogen source. There are two structurally dis...
Main Authors: | Joana Faria, Inês Loureiro, Nuno Santarém, Sandra Macedo-Ribeiro, Joana Tavares, Anabela Cordeiro-da-Silva |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
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Series: | PLoS Neglected Tropical Diseases |
Online Access: | http://europepmc.org/articles/PMC4714757?pdf=render |
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