A potent larvicidal agent against Aedes aegypti mosquito from cardanol

ABSTRACT Cardanol is a constituent of Cashew Nut Shell Liquid that presents larvicidal activity against Aedes aegypti. The isolation of cardanol is somewhat troublesome, however, in this work we describe an efficient and inexpensive method to obtain it as a pure material. The compound was used as st...

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Main Authors: DERISVALDO R. PAIVA, DÊNIS P. DE LIMA, NAGA P. AVVARI, EDUARDO J. DE ARRUDA, ISAIAS CABRINI, MARIA RITA MARQUES, EDSON A. DOS SANTOS, FRANCISCO C. BIAGGIO, DIEGO P. SANGI, ADILSON BEATRIZ
Format: Article
Language:English
Published: Academia Brasileira de Ciências
Series:Anais da Academia Brasileira de Ciências
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000200373&lng=en&tlng=en
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Summary:ABSTRACT Cardanol is a constituent of Cashew Nut Shell Liquid that presents larvicidal activity against Aedes aegypti. The isolation of cardanol is somewhat troublesome, however, in this work we describe an efficient and inexpensive method to obtain it as a pure material. The compound was used as starting material to make chemical transformation leading to saturated cardanol, epoxides and, halohydrins. These derivatives were tested for toxicity against Aedes aegypti larvae. The results showed that iodohydrins are very promising compounds for making commercial products to combat the vector mosquito larvae presenting a LC50 of 0.0023 ppm after 72 h of exposure.
ISSN:1678-2690