Inhibition of STAT3 signaling induces apoptosis and suppresses growth of lung cancer: good and bad

Abstract Signal transducer and activator of transcription 3 (STAT3) modulates a variety of genes involved in the regulation of critical functions, including cell proliferation, differentiation, apoptosis, angiogenesis, metastasis, and immunity. For many cancers, elevated levels of STAT3 signaling ha...

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Bibliographic Details
Main Authors: Ju-Hee Kang, Yeong-Su Jang, Ha Jung Lee, Chang-Yong Lee, Dong Yun Shin, Seung Hyun Oh
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Laboratory Animal Research
Subjects:
Online Access:https://doi.org/10.1186/s42826-019-0030-0