The role of surface charge of ISCOMATRIX nanoparticles on the type of immune response generated against Leishmaniasis in BALB/c mice

Objective(s): ISCOMATRIX vaccines have now been shown to induce strong antigen-specific cellular or humoral immune responses to a broad range of antigens of viral, bacterial, parasite or tumor. In the present study, we investigated the role of ISCOMATRIX charge in induction of a Th1 type of immune r...

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Bibliographic Details
Main Authors: Ahmad Mehravaran, Mahmoud Reza Jaafari, Seyed Amir Jalali, Ali Khamesipour, Mohsen Tafaghodi, Mansure Hojatizade, Ali Badieea
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-10-01
Series:Nanomedicine Journal
Subjects:
Online Access:http://nmj.mums.ac.ir/pdf_4956_a441c79e15ca18edef4bf5dd3c6446d4.html