Lumican Inhibits In Vivo Melanoma Metastasis by Altering Matrix-Effectors and Invadopodia Markers

It was reported that lumican inhibits the activity of metalloproteinase MMP-14 and melanoma cell migration in vitro and in vivo. Moreover, Snail triggers epithelial-to-mesenchymal transition and the metastatic potential of cancer cells. Therefore, the aim of this study was to examine the effect of l...

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Bibliographic Details
Main Authors: Konstantina Karamanou, Marco Franchi, Isabelle Proult, Romain Rivet, Demitrios Vynios, Stéphane Brézillon
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/4/841