A novel QSAR model for designing, evaluating,and predicting the anti-MES activity of new 1H-pyrazole-5-carboxylic acid derivatives

A novel QSAR model for designing, evaluating,and predicting the anti-MES activity of new 1H-pyrazole-5-carboxylic acid derivatives

A quantitative structure–activity relationship (QSAR) study was performed to develop a model that relates the structures of 62 compounds, which have activity against maximal electroshock induced seizure (MES), with their anti-MES activity. Molecular structures of the compounds were geometrically opt...

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Bibliographic Details
Main Authors:	Adedirin Oluwaseye, Adamu Uzairu, Gideon Shallangwa, Stephen Abechi
Format:	Article
Language:	English
Published:	Turkish Chemical Society 2017-07-01
Series:	Journal of the Turkish Chemical Society, Section A: Chemistry
Subjects:	: MES QSAR GFA Molecular docking Kennard-Stone algorithm
Online Access:	http://dergipark.gov.tr/jotcsa/issue/30155/304584

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