Spectrophotometric Determination of 4-Hydroxy-2-mercapto-6-methylpyrimidine Based on Aggregation of Colloidal Gold Nanoparticles

We report herein the development of a highly sensitive colorimetric method for the detection of 4-hydroxy-2-mercapto-6-methylpyrimidine (MTU) which acts as an anti-thyroid drug utilizing citrate capped gold nanoparticles (Au-NPs). This thiol-containing molecule exhibits intriguing affinity with Au-N...

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Bibliographic Details
Main Authors: M.Reza Hormozi-Nezhad, Sena Ghayyem
Format: Article
Language:English
Published: Iranian Chemical Society 2014-12-01
Series:Analytical and Bioanalytical Chemistry Research
Subjects:
Online Access:http://www.analchemres.org/article_7569_244fffeb1c034d3d3c929ce622e7ce06.pdf