Assessing protein immunogenicity with a dendritic cell line-derived endolysosomal degradome.

Assessing protein immunogenicity with a dendritic cell line-derived endolysosomal degradome.

The growing number of novel candidate molecules for the treatment of allergic diseases imposed a dramatic increase in the demand for animal experiments to select immunogenic vaccines, a pre-requisite for efficacy. Because no in vitro methods to predict the immunogenicity of a protein are currently a...

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Bibliographic Details
Main Authors: Matthias Egger, Alexander Jürets, Michael Wallner, Peter Briza, Silke Ruzek, Stefan Hainzl, Ulrike Pichler, Claudia Kitzmüller, Barbara Bohle, Christian G Huber, Fátima Ferreira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3040223?pdf=render

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http://europepmc.org/articles/PMC3040223?pdf=render

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