Brain Amide Proton Transfer Imaging of Rat With Alzheimer’s Disease Using Saturation With Frequency Alternating RF Irradiation Method

Brain Amide Proton Transfer Imaging of Rat With Alzheimer’s Disease Using Saturation With Frequency Alternating RF Irradiation Method

Amyloid-β (Aβ) deposits and some proteins play essential roles in the pathogenesis of Alzheimer’s disease (AD). Amide proton transfer (APT) imaging, as an imaging modality to detect tissue protein, has shown promising features for the diagnosis of AD disease. In this study, we chose 10 AD model rats...

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Bibliographic Details
Main Authors: Runrun Wang, Peidong Chen, Zhiwei Shen, Guisen Lin, Gang Xiao, Zhuozhi Dai, Bingna Zhang, Yuanfeng Chen, Lihua Lai, Xiaodan Zong, Yan Li, Yanyan Tang, Renhua Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
amide proton transfer
saturation with alternating frequency RF irradiation
chemical exchange saturation transfer
magnetic resonance imaging
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00217/full

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https://www.frontiersin.org/article/10.3389/fnagi.2019.00217/full

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