Multivariate approach for longitudinal analysis of brain metabolite levels from ages 5-11 years in children with perinatal HIV infection

Multivariate approach for longitudinal analysis of brain metabolite levels from ages 5-11 years in children with perinatal HIV infection

Treatment guidelines recommend that children with perinatal HIV infection (PHIV) initiate antiretroviral therapy (ART) early in life and remain on it lifelong. As part of a longitudinal study examining the long-term consequences of PHIV and early ART on the developing brain, 89 PHIV children and a c...

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Bibliographic Details
Main Authors: Noëlle van Biljon, Frances Robertson, Martha Holmes, Mark F Cotton, Barbara Laughton, Andre van der Kouwe, Ernesta Meintjes, Francesca Little
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:NeuroImage
Subjects:
Magnetic resonance spectroscopy (MRS)
Brain metabolites
Perinatal HIV infection
Longitudinal analysis
Multilevel mixed effect model (MMEM)
Correlated response model (CRM)
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811921003785

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http://www.sciencedirect.com/science/article/pii/S1053811921003785

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