Levofloxacin versus placebo for the prevention of tuberculosis disease in child contacts of multidrug-resistant tuberculosis: study protocol for a phase III cluster randomised controlled trial (TB-CHAMP)

Levofloxacin versus placebo for the prevention of tuberculosis disease in child contacts of multidrug-resistant tuberculosis: study protocol for a phase III cluster randomised controlled trial (TB-CHAMP)

Abstract Background Multidrug-resistant (MDR) tuberculosis (TB) presents a challenge for global TB control. Treating individuals with MDR-TB infection to prevent progression to disease could be an effective public health strategy. Young children are at high risk of developing TB disease following in...

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Bibliographic Details
Main Authors: James A. Seddon, Anthony J. Garcia-Prats, Susan E. Purchase, Muhammad Osman, Anne-Marie Demers, Graeme Hoddinott, Angela M. Crook, Ellen Owen-Powell, Margaret J. Thomason, Anna Turkova, Diana M. Gibb, Lee Fairlie, Neil Martinson, H. Simon Schaaf, Anneke C. Hesseling
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Trials
Subjects:
Tuberculosis
TB
Resistant
Trial
Prevention
Randomised
Online Access:http://link.springer.com/article/10.1186/s13063-018-3070-0

Internet

http://link.springer.com/article/10.1186/s13063-018-3070-0

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