Discovering novel SNPs that are correlated with patient outcome in a Singaporean cancer patient cohort treated with gemcitabine-based chemotherapy

Discovering novel SNPs that are correlated with patient outcome in a Singaporean cancer patient cohort treated with gemcitabine-based chemotherapy

Abstract Background Single Nucleotide Polymorphisms (SNPs) can influence patient outcome such as drug response and toxicity after drug intervention. The purpose of this study is to develop a systematic pathway approach to accurately and efficiently predict novel non-synonymous SNPs (nsSNPs) that cou...

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Bibliographic Details
Main Authors: Vachiranee Limviphuvadh, Chee Seng Tan, Fumikazu Konishi, Piroon Jenjaroenpun, Joy Shengnan Xiang, Yuliya Kremenska, Yar Soe Mu, Nicholas Syn, Soo Chin Lee, Ross A. Soo, Frank Eisenhaber, Sebastian Maurer-Stroh, Wei Peng Yong
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Cancer
Subjects:
Gemcitabine
NSCLC
Pharmacogenetics
SNPs
Patient outcome
Online Access:http://link.springer.com/article/10.1186/s12885-018-4471-x

Internet

http://link.springer.com/article/10.1186/s12885-018-4471-x

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