Synaptic Plasticity and Learning in Animal Models of Tuberous Sclerosis Complex
Tuberous sclerosis complex (TSC) is caused by a mutation of either the Tsc1 or Tsc2 gene. As these genes work in concert to negatively regulate the mammalian target of rapamycin (mTOR) kinase which is involved in protein translation, mutations of these genes lead to a disinhibited mTOR activity. Bot...
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2012-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2012/279834 |