Sodium Butyrate Modulates Mucosal Inflammation Injury Mediated by GPR41/43 in the Cecum of Goats Fed a High Concentration Diet

Sodium Butyrate Modulates Mucosal Inflammation Injury Mediated by GPR41/43 in the Cecum of Goats Fed a High Concentration Diet

Emerging data indicate that excessive short chain fatty acids can mediate the downstream mitogen-activated protein kinase pathways by activating G-protein coupled receptor 41/43 (GPR41/43) to initiate the inflammatory response. The current study was conducted to investigate if a high concentrate (HC...

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Bibliographic Details
Main Authors: Guangjun Chang, Nana Ma, Huanmin Zhang, Yan Wang, Jie Huang, Jing Liu, Hongyu Dai, Xiangzhen Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Physiology
Subjects:
SCFAs
GPR41/43
inflammation
cecum
epigenetic mechanism
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01130/full

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