Advances on the metabolism of cohesin in age-related chromosomal aneuploidy
Age-related chromosomal aneuploidy is associated with the reduction of cohesin in meiosis. There are many complicated factors affecting the metabolism of cohesion, including the hyperactive separase, abnormal Shugoshin protein degradation, oxidative damage, increased intracellular pH in oocytes, abn...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2019-01-01
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Series: | Reproductive and Developmental Medicine |
Subjects: | |
Online Access: | http://www.repdevmed.org/article.asp?issn=2096-2924;year=2019;volume=3;issue=4;spage=243;epage=246;aulast=Tian |