Advances on the metabolism of cohesin in age-related chromosomal aneuploidy

Age-related chromosomal aneuploidy is associated with the reduction of cohesin in meiosis. There are many complicated factors affecting the metabolism of cohesion, including the hyperactive separase, abnormal Shugoshin protein degradation, oxidative damage, increased intracellular pH in oocytes, abn...

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Bibliographic Details
Main Authors: Li-Yuan Tian, Bin Zhang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Reproductive and Developmental Medicine
Subjects:
Online Access:http://www.repdevmed.org/article.asp?issn=2096-2924;year=2019;volume=3;issue=4;spage=243;epage=246;aulast=Tian