Phosphorylation-Dependent Intra-Domain Interaction of the Cx37 Carboxyl-Terminus Controls Cell Survival

Phosphorylation-Dependent Intra-Domain Interaction of the Cx37 Carboxyl-Terminus Controls Cell Survival

Differential phosphorylation of the carboxyl-terminus of connexin 37 (Cx37-CT) regulates phenotypic switching between cell growth phenotypes (cell death, cell cycle arrest, proliferation). The specific phosphorylation events in the Cx37-CT that are necessary for these growth regulatory effects are c...

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Bibliographic Details
Main Authors: Nicole L. Jacobsen, Tasha K. Pontifex, Paul R. Langlais, Janis M. Burt
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cancers
Subjects:
gap junction
connexin
cell cycle
cell death
gating
phosphorylation
Online Access:https://www.mdpi.com/2072-6694/11/2/188

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