Microparticles Carrying Sonic Hedgehog Are Increased in Humans with Peripheral Artery Disease

Microparticles Carrying Sonic Hedgehog Are Increased in Humans with Peripheral Artery Disease

Sonic hedgehog (Shh) is a prototypical angiogenic agent with a crucial role in the regulation of angiogenesis. Experimental studies have shown that Shh is upregulated in response to ischemia. Also, Shh may be found on the surface of circulating microparticles (MPs) and MPs bearing Shh (Shh + MPs) ha...

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Bibliographic Details
Main Authors: Igor Giarretta, Ilaria Gatto, Margherita Marcantoni, Giulia Lupi, Diego Tonello, Eleonora Gaetani, Dario Pitocco, Roberto Iezzi, Addolorata Truma, Angelo Porfidia, Adriana Visonà, Paolo Tondi, Roberto Pola
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
sonic hedgehog
microparticles
peripheral artery disease
Online Access:https://www.mdpi.com/1422-0067/19/12/3954

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https://www.mdpi.com/1422-0067/19/12/3954

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