bin3C: exploiting Hi-C sequencing data to accurately resolve metagenome-assembled genomes

Abstract Most microbes cannot be easily cultured, and metagenomics provides a means to study them. Current techniques aim to resolve individual genomes from metagenomes, so-called metagenome-assembled genomes (MAGs). Leading approaches depend upon time series or transect studies, the efficacy of whi...

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Bibliographic Details
Main Authors: Matthew Z. DeMaere, Aaron E. Darling
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Genome Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13059-019-1643-1