Novel Tissue Level Effects of the Staphylococcus aureus Enterotoxin Gene Cluster Are Essential for Infective Endocarditis.

Superantigens are indispensable virulence factors for Staphylococcus aureus in disease causation. Superantigens stimulate massive immune cell activation, leading to toxic shock syndrome (TSS) and contributing to other illnesses. However, superantigens differ in their capacities to induce body-wide e...

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Bibliographic Details
Main Authors: Christopher S Stach, Bao G Vu, Joseph A Merriman, Alfa Herrera, Michael P Cahill, Patrick M Schlievert, Wilmara Salgado-Pabón
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4849672?pdf=render