Improved expansion of equine cord blood derived mesenchymal stromal cells by using microcarriers in stirred suspension bioreactors

Abstract Equine mesenchymal stromal cells (MSCs) are increasingly investigated for their clinical therapeutic utility. Such cell-based treatments can require cell numbers in the millions or billions, with conventional expansion methods using static T-flasks typically inefficient in achieving these c...

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Bibliographic Details
Main Authors: Erin L. Roberts, Tiffany Dang, Sarah I. M. Lepage, Amir Hamed Alizadeh, Tylor Walsh, Thomas G. Koch, Michael S. Kallos
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Journal of Biological Engineering
Online Access:http://link.springer.com/article/10.1186/s13036-019-0153-8