Efficient Cas9-based genome editing of Rhodobacter sphaeroides for metabolic engineering

Efficient Cas9-based genome editing of Rhodobacter sphaeroides for metabolic engineering

Abstract Background Rhodobacter sphaeroides is a metabolically versatile bacterium that serves as a model for analysis of photosynthesis, hydrogen production and terpene biosynthesis. The elimination of by-products formation, such as poly-β-hydroxybutyrate (PHB), has been an important metabolic engi...

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Bibliographic Details
Main Authors: Ioannis Mougiakos, Enrico Orsi, Mohammad Rifqi Ghiffary, Wilbert Post, Alberto de Maria, Belén Adiego-Perez, Servé W. M. Kengen, Ruud A. Weusthuis, John van der Oost
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Microbial Cell Factories
Subjects:
Rhodobacter sphaeroides
Cas9
Genome editing
PHB
Online Access:http://link.springer.com/article/10.1186/s12934-019-1255-1

Internet

http://link.springer.com/article/10.1186/s12934-019-1255-1

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