Variations of glaucine, quercetin and kaempferol contents in Nigella arvensis against Al2O3, NiO, and TiO2 nanoparticles
The present study was designed to determine the glaucine, quercetin and kaempferol contents in the root and shoot parts of Nigella arvensis, treated for 21 days with different concentrations of the nanoparticles (NPs), including titanium dioxide (TiO2), alumina (Al2O3) and nickel oxide (NiO) by high...
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doaj-a2eff3252f8c491995476571b5faa7942020-11-25T03:52:13ZengElsevierHeliyon2405-84402020-06-0166e04265Variations of glaucine, quercetin and kaempferol contents in Nigella arvensis against Al2O3, NiO, and TiO2 nanoparticlesMasoud Modarresi0Azam Chahardoli1Naser Karimi2Sima Chahardoli3Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, IranPharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran; Department of Biology, Faculty of Science, Razi University, Kermanshah, Iran; Corresponding author.Department of Biology, Faculty of Science, Razi University, Kermanshah, IranDepartment of Soil Science, Faculty of Agriculture, University of Zanjan, Zanjan, IranThe present study was designed to determine the glaucine, quercetin and kaempferol contents in the root and shoot parts of Nigella arvensis, treated for 21 days with different concentrations of the nanoparticles (NPs), including titanium dioxide (TiO2), alumina (Al2O3) and nickel oxide (NiO) by high-performance liquid chromatography (HPLC). Results showed a significant increase in the total flavonoid and total alkaloid content in treated plants. Glaucine content in shoot parts was significantly higher than the root parts. The highest amount of glaucine was obtained in shoots and roots exposed to NiONPs at concentrations of 1000 and 2500 mg/L with up to 3.2 and 2.6 fold increase compared to the control group, respectively. The maximum content of quercetin was observed in the shoot and root parts under 50 mg/L NiONPs with 2.2 and 1.8 fold increase compared to the control group, respectively. The kaempferol content was significantly decreased in all treatment, except for 1000 mg/L NiONPs treatment in the root parts, which was 2.9 fold higher than the control group. Apart from the toxic effects of some NPs, our findings suggest that the NPs at specific levels can be considered as new and appropriate elicitors for in vitro production and increasing the biosynthesis of secondary metabolites to use in pharmaceutical applications.http://www.sciencedirect.com/science/article/pii/S2405844020311099GlaucineNigella arvensisAl2O3NPsTiO2NPsNiONPsHPLC |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Masoud Modarresi Azam Chahardoli Naser Karimi Sima Chahardoli |
spellingShingle |
Masoud Modarresi Azam Chahardoli Naser Karimi Sima Chahardoli Variations of glaucine, quercetin and kaempferol contents in Nigella arvensis against Al2O3, NiO, and TiO2 nanoparticles Heliyon Glaucine Nigella arvensis Al2O3NPs TiO2NPs NiONPs HPLC |
author_facet |
Masoud Modarresi Azam Chahardoli Naser Karimi Sima Chahardoli |
author_sort |
Masoud Modarresi |
title |
Variations of glaucine, quercetin and kaempferol contents in Nigella arvensis against Al2O3, NiO, and TiO2 nanoparticles |
title_short |
Variations of glaucine, quercetin and kaempferol contents in Nigella arvensis against Al2O3, NiO, and TiO2 nanoparticles |
title_full |
Variations of glaucine, quercetin and kaempferol contents in Nigella arvensis against Al2O3, NiO, and TiO2 nanoparticles |
title_fullStr |
Variations of glaucine, quercetin and kaempferol contents in Nigella arvensis against Al2O3, NiO, and TiO2 nanoparticles |
title_full_unstemmed |
Variations of glaucine, quercetin and kaempferol contents in Nigella arvensis against Al2O3, NiO, and TiO2 nanoparticles |
title_sort |
variations of glaucine, quercetin and kaempferol contents in nigella arvensis against al2o3, nio, and tio2 nanoparticles |
publisher |
Elsevier |
series |
Heliyon |
issn |
2405-8440 |
publishDate |
2020-06-01 |
description |
The present study was designed to determine the glaucine, quercetin and kaempferol contents in the root and shoot parts of Nigella arvensis, treated for 21 days with different concentrations of the nanoparticles (NPs), including titanium dioxide (TiO2), alumina (Al2O3) and nickel oxide (NiO) by high-performance liquid chromatography (HPLC). Results showed a significant increase in the total flavonoid and total alkaloid content in treated plants. Glaucine content in shoot parts was significantly higher than the root parts. The highest amount of glaucine was obtained in shoots and roots exposed to NiONPs at concentrations of 1000 and 2500 mg/L with up to 3.2 and 2.6 fold increase compared to the control group, respectively. The maximum content of quercetin was observed in the shoot and root parts under 50 mg/L NiONPs with 2.2 and 1.8 fold increase compared to the control group, respectively. The kaempferol content was significantly decreased in all treatment, except for 1000 mg/L NiONPs treatment in the root parts, which was 2.9 fold higher than the control group. Apart from the toxic effects of some NPs, our findings suggest that the NPs at specific levels can be considered as new and appropriate elicitors for in vitro production and increasing the biosynthesis of secondary metabolites to use in pharmaceutical applications. |
topic |
Glaucine Nigella arvensis Al2O3NPs TiO2NPs NiONPs HPLC |
url |
http://www.sciencedirect.com/science/article/pii/S2405844020311099 |
work_keys_str_mv |
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