In vivo anti‐V‐ATPase antibody treatment delays ovarian tumor growth by increasing antitumor immune responses

Tumor acidity is the key metabolic feature promoting cancer progression and is modulated by pH regulators on a cancer cell's surface that pump out excess protons/lactic acid for cancer cell survival. Neutralizing tumor acidity improves the therapeutic efficacy of current treatments including im...

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Bibliographic Details
Main Authors: Arpita Kulshrestha, Gajendra K. Katara, Safaa A. Ibrahim, Valerie E. Riehl, Sylvia Schneiderman, Mahmood Bilal, Alexandria N. Young, Shayna Levine, Sara Fleetwood, James Dolan, Alice Gilman‐Sachs, Kenneth D. Beaman
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Molecular Oncology
Subjects:
Online Access:https://doi.org/10.1002/1878-0261.12782