Spatiotemporal correlations between cytosolic and mitochondrial Ca(2+) signals using a novel red-shifted mitochondrial targeted cameleon.

The transfer of Ca(2+) from the cytosol into the lumen of mitochondria is a crucial process that impacts cell signaling in multiple ways. Cytosolic Ca(2+) ([Ca(2+)](cyto)) can be excellently quantified with the ratiometric Ca(2+) probe fura-2, while genetically encoded Förster resonance energy trans...

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Bibliographic Details
Main Authors: Markus Waldeck-Weiermair, Muhammad Rizwan Alam, Muhammad Jadoon Khan, Andras T Deak, Neelanjan Vishnu, Felix Karsten, Hiromi Imamura, Wolfgang F Graier, Roland Malli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23029314/pdf/?tool=EBI